Cross Matching

blood products blood safety cross matching patient safety perioperativenursing safety Nov 24, 2023
So Rahul needs a blood transfusion. How can we be sure his antibodies will not attack the new blood cells and cause a serious transfusion reaction? 😡‍πŸ’«
 
πŸ‘‡ Here’s how πŸ‘‡
 
Crossmatching is performed so the lab can select and send you blood that is compatible for transfusion. The main concern is whether Rahul’s serum will attack the donor red cells. 🩸πŸ§ͺ
 
A secondary concern is whether the donor serum contains antibodies that will attack Rahul’s red cells. But as we are only giving Rahul a small dose of donor serum, this is less important.
 
Here are the main steps:
 
πŸ‘‰πŸ½ Rahul’s blood is first tested for ABO blood group and RhD status.
πŸ‘‰πŸ½ Then a bag that matches (or is compatible) is chosen.
πŸ‘‰πŸ½ A few drops of Rahul’s serum is mixed with a few drops of the donor blood.
πŸ‘‰πŸ½ The mixture is warmed to body temperature.
πŸ‘‰πŸ½ A few drops of Anti-human Globulin are added to screen for antibodies
πŸ‘‰πŸ½ The sample is spun in a centrifuge
πŸ‘‰πŸ½ The sample is examined for agglutination.
πŸ‘‰πŸ½ No agglutination means that Rahul can safely receive his blood transfusion!
 
Build knowledge. βœ…
Improve safety. βœ…
 
Ref
https://laboratorytests.org/cross-matching/
 

 

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