Cross Matching
Nov 24, 2023![](https://kajabi-storefronts-production.kajabi-cdn.com/kajabi-storefronts-production/file-uploads/blogs/2147545446/images/e8daa0a-8dd0-4578-0fda-7eaa4f1a5e33_Concept_Series_website_YouTube_Banner_.png)
So Rahul needs a blood transfusion. How can we be sure his antibodies will not attack the new blood cells and cause a serious transfusion reaction? π΅π«
π Here’s how π
Crossmatching is performed so the lab can select and send you blood that is compatible for transfusion. The main concern is whether Rahul’s serum will attack the donor red cells. π©Έπ§ͺ
A secondary concern is whether the donor serum contains antibodies that will attack Rahul’s red cells. But as we are only giving Rahul a small dose of donor serum, this is less important.
Here are the main steps:
ππ½ Rahul’s blood is first tested for ABO blood group and RhD status.
ππ½ Then a bag that matches (or is compatible) is chosen.
ππ½ A few drops of Rahul’s serum is mixed with a few drops of the donor blood.
ππ½ The mixture is warmed to body temperature.
ππ½ A few drops of Anti-human Globulin are added to screen for antibodies
ππ½ The sample is spun in a centrifuge
ππ½ The sample is examined for agglutination.
ππ½ No agglutination means that Rahul can safely receive his blood transfusion!
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Ref
https://laboratorytests.org/cross-matching/